PROCESS FOR THE PREPARATION OF MONO-PROTECTED [alpha],[omega]-DIAMINO ALKANES

PROCESS FOR THE PREPARATION OF MONO-PROTECTED [alpha],[omega]-DIAMINO ALKANES

The present invention relates to a process for the synthesis of mono-protected [alpha],[omega]-diamino alkanes, the use of the process in a process for the synthesis of a linker drug comprising an [alpha],[omega]-diamino alkane moiety and the use of the process of the present invention in a process...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: MENGE WIRO MICHAEL PETRUS BERNARDUS
Format: Patent
Sprache:chi ; eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention relates to a process for the synthesis of mono-protected [alpha],[omega]-diamino alkanes, the use of the process in a process for the synthesis of a linker drug comprising an [alpha],[omega]-diamino alkane moiety and the use of the process of the present invention in a process for preparing an antibody-drug conjugate comprising an [alpha],[omega]-diamino alkane moiety. 本发明涉及用于合成单保护的α，ω-二氨基烷烃的方法、所述方法在用于合成包含α，ω-二氨基烷烃部分的接头药物的方法中的用途、以及本发明的方法在用于制备包含α，ω-二氨基烷烃部分的抗体-药物缀合物的方法中的用途。