Method for optimizing freeze-drying curve of freeze-dried adenosine triphosphate preparation for injection

The invention discloses a method for optimizing a freeze-drying curve of a freeze-dried adenosine triphosphate preparation for injection. The technical solution of the invention comprises the steps ofselecting reasonable pre-freezing temperature, sublimation temperature and vacuum degree during dryi...

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Bibliographische Detailangaben
Hauptverfasser: LIU NAISHAN, DONG HUIYI, FU YU
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a method for optimizing a freeze-drying curve of a freeze-dried adenosine triphosphate preparation for injection. The technical solution of the invention comprises the steps ofselecting reasonable pre-freezing temperature, sublimation temperature and vacuum degree during drying to improve characters of the freeze-dried product. The quality standard of the preparation conforms to various indexes specified by the National Drug Standards. The method of the invention has the advantages of stable characters and attractive appearance of the freeze-dried product. 本发明公开了一种注射用三磷酸腺苷冻干制剂冻干曲线优化的方法,技术方案是选择合理的预冻和升华温度以及干燥时的真空度来提高冻干品的性状。其质量标准符合国家药品标准所规定的各项指标,本发明方法具有冻干品性状稳定、外观美观等优点。