Application of ferulamide compound in preparation of anticomplementary drugs

The invention belongs to the technical field of preparation of traditional Chinese medicine and relates to application of a ferulamide compound in the preparation of anticomplementary drugs. the ferulamide compound n-trans-feruloyl tyramine, compound lyciumamide D and compound lyciumamide B shown as formulas below are isolated and extracted from the whole plant of Polygonum chinensis Linn of the family Polygonaceae through activity-oriented separation; anticomplementary activity evaluation tests show that the compounds can well inhibit both typical and alternative pathways of the complementarysystem, wherein the inhibitory action (CH50) on the typical pathway is 0.35-0.92 mM, and the inhibitory action (AP50) on the alternative pathway is 0.40-1.36 mM. The compounds herein can be preparedinto anticomplementary drugs and drugs to treat complement-related diseases. 本发明属于中药制药技术领域，涉及阿魏酸酰胺类化合物及其在制备抗补体药物中的用途。本发明采用活性导向分离方法从蓼科(Polygonaceae)植物火炭母(Polygonum chinensis Linn)的全草中分离提取到下式所示的阿魏酸酰胺类化合物n-tans-feruloyl tyramine，