Amurensin H derivative, preparation method thereof, medicine composition and application

The invention discloses a murensin H derivative with anti-inflammatory activity, a preparation method and the anti-inflammatory activity thereof, and in particular relates to a 3,4-diaryl benzofuran derivative, a 3,4-diaryl dihydrobenzofuran derivative, and a medically acceptable salt shown as general formula (I), general formula (II) and general formula (III) (the general formulas are shown in the description). The invention further discloses the application of the compound monomer or the medicine composition to the preparation of therapeutic drugs or health care products of inflammatory immunization related diseases. 本发明公开了一类具有抗炎活性的葡萄藤戊素(Amurensin H)衍生物、其制法及其抗炎活性。具体涉及到一类如通式(I)、(II)和(III)所示的3,4-二芳基苯并呋喃衍生物和3,4-二芳基苯并二氢呋喃衍生物及其医学上可接受的盐。公开了该类化合物单体或药用组合物在制备炎症免疫相关疾病治疗药物或保健品中的应用。