Furan-and thiophenecarbothioamide derivatives, their preparation and their use as inhibitors of replication of HIV-1 and HIV-1 mutants

Furan-and thiophenecarbothioamide derivatives, their preparation and their use as inhibitors of replication of HIV-1 and HIV-1 mutants

Compounds of the formula (I) wherein X is O or S, useful for the inhibition of the replication of HIV-1 and reverse transcriptase mutants thereof, in vitro and in vivo.

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Bibliographische Detailangaben
Hauptverfasser: E.M. OSIKA, W.G. BROUWER, B.J. PIERCE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Compounds of the formula (I) wherein X is O or S, useful for the inhibition of the replication of HIV-1 and reverse transcriptase mutants thereof, in vitro and in vivo.