一种突释型丝素蛋白-PEO-纳米金抗菌膜及制备方法

本发明公开一种突释型丝素蛋白-PEO-纳米金抗菌膜及其制备方法，突释型丝素蛋白-PEO-纳米金抗菌膜中Au-DAPT-NPs的突释时间点为5分钟；制成突释型丝素蛋白-PEO-纳米金抗菌膜的原料包括直径为4-6nm的Au-DAPT-NPs纳米金颗粒、丝素蛋白的浓度为16％-20％的丝素蛋白溶液。突释型丝素蛋白-PEO-纳米金抗菌膜的制备方法包括丝素蛋白浓度为16-20％丝素蛋白溶液的制备、Au-DAPT-NPs抗菌纳米金溶液的制备等。本发明克服了纳米抗菌材料在固态膜中释放缓慢、以及含有纳米的抗菌材料需要采用静电纺丝等复杂耗时方法制备的缺陷，制备方法简单。 The invention discloses a sudden-release silk fibroin-PEO-nanogold antimicrobial film and a preparation method thereof. The sudden-release time of Au-DAPT-NPs of the sudden-release silk fibroin-PEO-nanogold antimicrobial film is 5 minutes, and raw materials for preparing the sudden-release silk fibroin-PEO-nanogold antimicrobial film comprise Au-DAPT-NPs nanogold particles with diameters of 4-6 nmand a silk fibroin solution with concentration of 16%-20%. The preparation method of the sudden-release silk fibroin-PEO-nanogold antimicrobial film comprises preparation of the silk fibroin solutionwith concentration of 16%-20% and preparation of an Au-DAPT-NPs antimicrobial nanogold solution and the like. The film overcomes the defects of s