TWO-LAYER TOPICAL THERAPEUTIC SYSTEM

The invention relates to a topical therapeutic system which comprises: a backing layer; an active ingredient-containing matrix layer which contains at least one active ingredient, at least one permeation enhancer, at least one non-occlusive adhesive, at least one antioxidant and at least one crosslinking agent; and an occlusion-producing layer that contains at least one adhesive and that is located between the active ingredient-containing matrix layer and the backing layer. 本文描述局部治疗系统，包含背衬层，含活性成分的基质层，其含有至少一种活性成分、至少一种渗透性增强剂、至少一种非闭合性粘合剂、至少一种抗氧化剂和至少一种交联剂，以及含至少一种粘合剂的致闭合层，该层位于含活性成分的基质层与背衬层之间。