Application of diosmetin in preparation of drugs for treating pulmonary fibrosis

The invention provides application of diosmetin in the preparation of drugs for treating pulmonary fibrosis. The structure of diosmetin is shown as formula (I). An experiment proves that diosmetin hasa good effect on pulmonary fibrosis, does not cause adverse reaction, and can retard bleomycin-induc...

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Hauptverfasser: GAO SHAOYAN, DENG RUXIA, QI MIN, KANG HONG, YU HAIYAN, CUI YUNYAO, WEI YIYING, LI LIXIN, YANG CHENG, ZHOU HONGGANG, SHAO SHUAIBO, RAO ZIHE, BAI JIAKUN, YANG WEI, LI XIAOHE, DAI TINGTING, GAO JINGJING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides application of diosmetin in the preparation of drugs for treating pulmonary fibrosis. The structure of diosmetin is shown as formula (I). An experiment proves that diosmetin hasa good effect on pulmonary fibrosis, does not cause adverse reaction, and can retard bleomycin-induced pulmonary fibrosis in mice, thus having a good application prospect in treating, retarding or improving pulmonary fibrosis. 本发明提供了一种香叶木素在制备用于治疗肺纤维化疾病的药物中的应用,其中,香叶木素的结构如下式(I)所示:通过实验证明,香叶木素对肺纤维化有良好的功效,无不良反应,可减缓博莱霉素诱导的小鼠肺纤维化,在治疗、缓解或改善肺纤维化疾病方面具有良好的应用前景。