Cytoglobin-human lactoferricin fusion protein, gene and application

The invention discloses a cytoglobin-human lactoferricin fusion protein. The protein is characterized in that the fusion protein is formed by the serial connection of cell penetrating peptide (TAT), cytoglobin (Cytoglobin, CYGB) and the (human Lactoferricin, hLFcin); the fusion protein can be secret...

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Bibliographische Detailangaben
Hauptverfasser:	XIAO GUIQING, DONG LE, DUAN XUNWEI, CHEN HONGBIN, DAI CONGJIE, YANG BINHUANG, YUAN JIANJUN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL RIPENING OF FRUIT OR VEGETABLES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FOODS OR FOODSTUFFS HUMAN NECESSITIES METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PRESERVING, e.g. BY CANNING, MEAT, FISH, EGGS, FRUIT,VEGETABLES, EDIBLE SEEDS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS THE PRESERVED, RIPENED, OR CANNED PRODUCTS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention discloses a cytoglobin-human lactoferricin fusion protein. The protein is characterized in that the fusion protein is formed by the serial connection of cell penetrating peptide (TAT), cytoglobin (Cytoglobin, CYGB) and the (human Lactoferricin, hLFcin); the fusion protein can be secreted outside a cell by using the TAT, and therefore purification is convenient; the expression of thelactoferricin is driven by using the CYGB, and the inhibition on a host strain is relieved; the storage stability of antibacterial peptide is increased with the help of the oxidation resistance of theCYGB. The fusion protein can achieve the scale production of the TAT-CYGB-hLFcin fusion protein, complicated procedures of Linker designing of the fusion protein is avoided, the method for purifyingthe fusion protein is simplified by using the stable characteristics of the fusion protein, and the fusion protein can be used as an aquatic product preservative and can be applied to the field of aquatic product fresh keeping.