Application of toddalolactone in preparation of drugs for treatment of pulmonary fibrosis

The invention provides application of toddalolactone in preparation of drugs for treatment of pulmonary fibrosis. The structure of toddalolactone is shown in the description. The toddalolactone has agood effect on pulmonary fibrosis without adverse reactions. Bleomycin-induced pulmonary fibrosis in...

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Bibliographische Detailangaben
Hauptverfasser:	DENG RUXIA, QI MIN, XU CAN, YU HAIYAN, CUI YUNYAO, WEI YIYING, LI LIXIN, HUANG KAI, YANG CHENG, ZHOU HONGGANG, SHAO SHUAIBO, BAI JIAKUN, YANG WEI, LI XIAOHE, GAO JINGJING, DAI TINGTING
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides application of toddalolactone in preparation of drugs for treatment of pulmonary fibrosis. The structure of toddalolactone is shown in the description. The toddalolactone has agood effect on pulmonary fibrosis without adverse reactions. Bleomycin-induced pulmonary fibrosis in mice can be relieved, and the toddalolactone has good application prospects in the treatment, alleviation or improvement of pulmonary fibrosis. 本发明提供了一种毛两面针素在制备用于治疗肺纤维化疾病的药物中的应用，所述毛两面针素的结构如下式(I)所示：本发明所述的毛两面针素对肺纤维化有良好的功效，无不良反应，可减缓博莱霉素诱导的小鼠肺纤维化，在治疗、缓解或改善肺纤维化疾病方面具有良好的应用前景。