ANTI-APOC3 ANTIBODIES AND METHODS OF USE THEREOF

The invention provides antibodies that specifically bind to ApoC3 (e.g., human ApoC3) and antagonize ApoC3 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleicacids encoding these antibodies, expression vectors and host cells for making these antibodies, and m...

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Bibliographische Detailangaben
Hauptverfasser:	DASILVA-JARDINE PAUL, DE HAARD HANS, LANDRO JAMES A
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides antibodies that specifically bind to ApoC3 (e.g., human ApoC3) and antagonize ApoC3 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleicacids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies. 本公开提供了特异性结合ApoC3(例如人ApoC3)并拮抗ApoC3功能的抗体。还提供了包含这些抗体的药物组合物，编码这些抗体的核酸，用于制备这些抗体的表达载体和宿主细胞，以及使用这些抗体治疗受试者的方法。