Application of cimicifugin in preparation of medicines for treating pulmonary fibrosis diseases

The invention provides application of cimicifugin in preparation of medicines for treating pulmonary fibrosis diseases. The structure of the cimicifugin is shown in a formula (I), and the formula (I)is described in the description. Research shows that the cimicifugin has a good effect on pulmonary f...

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Hauptverfasser: GAO SHAOYAN, LIU RUI, LI HUIYING, QI MIN, JIANG QIUYAN, LI LIXIN, SUN RUIQIU, HUANG KAI, ZHOU HONGGANG, YANG CHENG, WANG YANHUA, LI XIAOHE, GAO JINGJING, MA LING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides application of cimicifugin in preparation of medicines for treating pulmonary fibrosis diseases. The structure of the cimicifugin is shown in a formula (I), and the formula (I)is described in the description. Research shows that the cimicifugin has a good effect on pulmonary fibrosis, has no adverse effects, and can slow down bleomycin-induced pulmonary fibrosis in mice, thus having a good application prospect in treatment, relief or improvement of the pulmonary fibrosis diseases. 本发明提供了一种升麻素在制备用于治疗肺纤维化疾病的药物中的应用,其中,升麻素的结构如下式(I)所示:本发明的研究表明,升麻素对肺纤维化有良好的功效,无不良反应,可减缓博莱霉素诱导的小鼠肺纤维化,在治疗、缓解或改善肺纤维化疾病方面具有良好的应用前景。