3D printed silk protein hydrogel and preparation method thereof

The invention provides a preparation method of 3D printed silk protein hydrogel. The preparation method includes the following steps: preparing pre-crosslinked silk protein hydrogel and 3D printed silk protein hydrogel, and specifically includes adding double-bond modified cyclodextrin and a photoinitiator into a silk protein solution, stirring to obtain single-network cross-linked silk protein hydrogel, and irradiating the single-network cross-linked silk protein hydrogel by UV light to form the pre-crosslinked silk protein hydrogel; crosslinking tyramine radicals on molecular chains of the cyclodextrin and silk protein in fiber filaments through 3D printing, and performing layer-by-layer stacking to form the 3D printed silk protein hydrogel. The invention further provides the 3D printedsilk protein hydrogel. The preparation method of the 3D printed silk protein hydrogel can effectively solve the problem of inter-layer separation of the 3D printed silk protein hydrogel, the obtainedsilk protein hydrogel is b