NOVEL IMIDAZOPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER

The present invention relates to a novel imidazopyridine derivative, a method for preparing same, and a pharmaceutical composition containing same as an active ingredient for preventing or treating cancer. The novel imidazopyridine derivative according to the present invention, a stereoisomer thereo...

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Hauptverfasser: KO YI-KYUNG, KIM NAM-DOO, BAE JAE-HYUN, LEE SUNG-WOO, LEE SUN-JOO, CHO JOONG-HEUI, JANG TAE-HO, LEE YOUN-HO, KIM SHIN-AE, KO EUN-HWA, CHOI HWAN-GEUN, LEE SEUNG-YEON, YOON SUK-KYOON, KIM HYUN-KYOUNG, SONG JAE-YOUNG, KIM SANG-BUM, PARK JIN-HEE, KANG SEOCK-YONG, RYU HEE-YOON, CHOI DONG-KYU, LEE SUN-HWA, MIN SANG-HYUN, HONG EUN-MI, KIM SO-YOUNG, SON JUNG-BEOM, KIM DA-YEA, HONG SEONG-HO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to a novel imidazopyridine derivative, a method for preparing same, and a pharmaceutical composition containing same as an active ingredient for preventing or treating cancer. The novel imidazopyridine derivative according to the present invention, a stereoisomer thereof, and pharmaceutically acceptable salts thereof can effectively inhibit cancer-related kinase, areexcellent in inhibiting proliferation of cancer cells in a cancer cell line, and effectively inhibit proliferation of cancer cells (cancer cell apoptosis) in a cancer cell heterograft model, and thuscan be useful as a pharmaceutical composition containing same as an active ingredient for preventing or treating cancer. Also, the novel imidazopyridine derivative according to the present invention,the stereoisomer thereof, and the pharmaceutically acceptable salts thereof can effectively inhibit Src and Fyn, thereby being useful as a pharmaceutical composition for preventing or treating relateddiseases, and in particular