Thyroid cancer related markers and application thereof

The invention discloses application of GGTLC3 and LINC02560 genes in the preparation of medicine for treating thyroid cancers. The medicine targets the GGTLC3 and LINC02560 genes. The invention provides a siRNA molecule for treating the thyroid cancers. The siRNA molecule comprises siRNA for inhibit...

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Hauptverfasser:	YAO GUANGYIN, YANG LONGYAN, SUN RONGXIN, LI LI, XIONG HUI, ZHAO DONG, JI ZHILI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention discloses application of GGTLC3 and LINC02560 genes in the preparation of medicine for treating thyroid cancers. The medicine targets the GGTLC3 and LINC02560 genes. The invention provides a siRNA molecule for treating the thyroid cancers. The siRNA molecule comprises siRNA for inhibiting the expression of the GGTLC3 and LINC02560 genes. The invention discloses molecular markers GGTLC3 and LINC02560 related to the thyroid cancers and application of an inhibitor of the markers in the preparation of the medicine for treating the thyroid cancers. A new idea is provided for the clinical treatment of the thyroid cancers, and a new direction is provided for the gene treatment of the thyroid cancers. 本发明公开了GGTLC3和LINC02560基因在制备治疗甲状腺癌的药物中的应用，所述药物靶向GGTLC3和LINC02560基因；以及提供种治疗甲状腺癌的siRNA分子，所述的siRNA分子包括抑制GGTLC3和LINC02560基因表达的siRNA。本发明发现了种与甲状腺癌相关的分子标记物GGTLC3和LINC02560，以及该标志物的抑制剂在制备治疗甲状腺癌药物中应用；本发明为临床治疗甲状腺癌提供了新的思路，为研究甲状腺癌的基因治疗提供了新的方向。