Targeted TSPO (Transport protein) magnetic resonance imaging contrast agent and preparation method thereof

The invention relates to a targeted TSPO (Transport protein) magnetic resonance imaging contrast agent and a preparation method thereof, and aims to solve the problem of low imaging space resolution in the prior art. The method comprises the following steps: a step I of preparing CB86-DTPAA through the a substep (1) of adding DMSO and DTPAA into a bottle wrapped by tin foil paper, additionally slowly adding CB86 in batches and simultaneously stirring, a substep (2) of adding triethylamine, sealing the bottle, placing the bottle on a magnetic heating stirrer and performing a light-shielded reaction, a substep (3) of placing the bottle in a refrigerator for freeze-drying over a night, taking the bottle out of the refrigerator next day, placing the bottle on a freeze dryer for dewatering, re-dissolving a freeze-dried product in pure water, continuously performing freeze-drying over a night and repeatedly performing above actions to obtain powder and a substep (4) of purifying and then drying by distillation to o