Omeprazole compound preparation

The invention relates to an omeprazole compound preparation, and belongs to the field of pharmaceutical preparations. The omeprazole compound preparation is prepared from active ingredients of omeprazole and smiglabrin and pharmaceutically acceptable auxiliary materials. The joint use of the omeprazole and the smiglabrin for treating peptic ulcer is studied for the first time, it is found througheffect experiments that a synergistic effect can be generated when the omeprazole and the smiglabrin are jointly used for treating gastric ulcer and duodenal ulcer, the proportion of the omeprazole tothe smiglabrin for drug combination is further optimized and screened, and the proportion range of the omeprazole to the smiglabrin is determined to be from 4 : 1 to 1 : 2. 本发明涉及奥美拉唑复方制剂，属于药物制剂领域。本发明提供了种奥美拉唑复方制剂，活性成分由奥美拉唑和赤土茯苓苷组成，还包括药学上可接受的辅料。本发明首次对奥美拉唑与赤土茯苓苷联合用于治疗消化性溃疡进行研究，通过效果试验发现，奥美拉唑与赤土茯苓苷联合用于治疗胃溃疡和十二指肠溃疡时能够产生协同增效作用，本发明进步对奥美拉唑与赤土茯苓苷联合用药的比例进行了优化筛选，确定两者的比例范围为4:1-1:2。