METHODS AND KITS FOR CELL ACTIVATION

Provided are methods and kits for activating T cells, the method comprising providing a population of T cells, adding a plurality of first agents, where the first agent comprises a T-cell activator and a first binder moiety, and adding a second agent comprising a plurality of capture oligomers, wher...

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Bibliographische Detailangaben
Hauptverfasser: BROWN MARTIN JAMES, SOOD ANUP, CHAUDHURI PADMAPARNA, KOVACS ERNEST WILLIAM, SMITH REGINALD DONOVAN, LOGHIN EVELINA ROXANA, CHADWICK CHRYSTAL MAE, KESKAR VANDANA
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Provided are methods and kits for activating T cells, the method comprising providing a population of T cells, adding a plurality of first agents, where the first agent comprises a T-cell activator and a first binder moiety, and adding a second agent comprising a plurality of capture oligomers, where at least a segment of at least one of the plurality of capture oligomers is capable of associatingwith the first binder moiety. The method further comprises incubating the population of T cells, whereby at least a portion of the population of T cells is activated. 本文中提供了活化免疫细胞的方法。该方法包括提供免疫细胞群,并使该免疫细胞群与第试剂和第二试剂接触。该第试剂包括连接到第结合子部分上的免疫细胞激活剂,并且该第二试剂包括至少种捕获低聚物。该至少种捕获低聚物能够与该第结合子部分缔合。还提供了用于活化免疫细胞的试剂盒。