COMPOSITIONS AND METHODS FOR SELECTIVE GI TRACT DELIVERY

A composition is hereby provided. The present composition comprises one or more micro-sized particles in the form of a core-shell. The core comprises an active agent and ingredients subject to pH-triggered dissolution, enzymatically-degradable ingredients and/or water- insoluble ingredients. The shell comprises one or more ingredients being characterized as enteric ingredients, enzymatically-degradable, and as water- insoluble ingredients. The particles may be dispersed in a liquid or other non-dry composition. 本文提供了种组合物。本组合物包括核壳形式的种或多种微米尺寸的颗粒。核包括活性剂和经历pH触发溶解的成分、酶可降解成分和/或水不溶性成分。壳包括种或多种成分，其表征为肠溶成分、酶可降解的并且水不溶性的成分。颗粒可以分散在液体或其它非干燥组合物中。