Bifunctional gold @ polypeptide nanocomposite and preparation method and application thereof

The invention relates to a bifunctional gold @ polypeptide nanocomposite and an application thereof. According to the bifunctional gold @ polypeptide nanocomposite and the application thereof, adhesion polypeptide is modified to the surface of a gold nanoparticle; and the detection is combined with...

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Bibliographische Detailangaben
Hauptverfasser: FENG YONGHAI, LIU LEI, JIN HANGSHUAI, CHEN QINGYU, GUI HANMENG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a bifunctional gold @ polypeptide nanocomposite and an application thereof. According to the bifunctional gold @ polypeptide nanocomposite and the application thereof, adhesion polypeptide is modified to the surface of a gold nanoparticle; and the detection is combined with photo-thermal therapy, so that the defects of poor binding property of between a photo-thermal agentand bacteria and poor response of SPR bacteria which exist currently are overcome, the photo-thermal conversion efficiency is improved, and the bacteria can be sensitively and efficiently detected and killed within a short time. 本发明涉及种双功能的金@多肽纳米复合材料及其用途。将粘附性多肽修饰到金纳米粒子表面。通过将检测与光热治疗相结合,解决目前光热剂与细菌结合性差,SPR细菌响应性差的缺点,提高其光热转换效率,可在短时间内灵敏,高效的检测和杀死细菌。