Method for surface enhanced Raman scattering detection

The embodiment of the invention discloses a method for surface enhanced Raman scattering detection. The method comprises the following step: preparing core-shell structures of silver core silicon dioxide shells deposited in a nano pore array on an AAO template. When the silver core silicon dioxide shells are taken as a substrate for surface enhanced Raman spectra, the core-shell structures form octahedral interstices, tetrahedral interstices or other irregular interstices like crystal structures in the stacking process. The interstices can form attachment points of probe molecules. As pore wall of the nano pore array on the AAO template is transparent and the shells of the core-shell structures are transparent, incident Raman detection laser can be directly focused to inner cores of the core-shell structures near the probe molecules to enhance the Raman scattering signals of the probe molecules, so that efficient surface enhanced Raman scattering signals are acquired. 本发明实施例公开了种进行表面增强拉曼散射检测的方法，制备得到在AAO模板上纳米孔洞