IDO1 inhibitor and application thereof

The invention provides an IDO1 inhibitor and use thereof in the preparation of anti-tumor drugs, belonging to the technical field of pharmacy. The invention discloses a compound represented by a formula (I) (shown in the description) as well as a stereochemistry isomer or a solvate or pharmaceutical...

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Bibliographische Detailangaben
Hauptverfasser: WANG FEI, LI SHENG, ZHOU ZONGYUAN, EMMANUEL MOFTI, ZHANG GUOLIN, FU NAIJIE
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention provides an IDO1 inhibitor and use thereof in the preparation of anti-tumor drugs, belonging to the technical field of pharmacy. The invention discloses a compound represented by a formula (I) (shown in the description) as well as a stereochemistry isomer or a solvate or pharmaceutically acceptable salt of the compound. The compound or the stereochemistry isomer or the solvate or thepharmaceutically acceptable salt of the compound represents an inhibiting effect to the activity of IDO1. The compound can be taken as the IDO1 inhibitor to be applied to the preparation of anti-tumor drugs. 本发明提供了种IDO1抑制剂及其在制备抗肿瘤药物中的用途,属于药学技术领域。本发明公开了种式(Ⅰ)所示化合物、或其立体化学异构体,或其溶剂合物、或其药学上可接受的盐。本发明公开的化合物、或其立体化学异构体,或其溶剂合物、或其药学上可接受的盐表现出对IDO1活性的抑制作用。可作为IDO1抑制剂,应用于制备抗肿瘤药物。