Nanometer composite anti-adhesion surgical mesh and preparation method thereof

The invention relates to a nanometer composite anti-adhesion surgical mesh and a preparation method thereof. The preparation method comprises the following steps: compounding a warp mesh and a nanofiber membrane by virtue of electrostatic spinning so as to prepare the nanometer composite anti-adhesi...

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Bibliographische Detailangaben
Hauptverfasser: ZHU XIAOQIAN, SHAO GUANGWEI, JIANG JINHUA, LIU YINING, ZHANG LEI, SHEN JINGYA, YU QINGHUA, SHAO HUIQI, CHEN NANLIANG, XU XIANGFEI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a nanometer composite anti-adhesion surgical mesh and a preparation method thereof. The preparation method comprises the following steps: compounding a warp mesh and a nanofiber membrane by virtue of electrostatic spinning so as to prepare the nanometer composite anti-adhesion surgical mesh, wherein an electrostatic spinning solution for electrostatic spinning is mainly composed of collagens, PEO, hexafluoroisopropanol and acetic acid; and the warp mesh is made from polypropylene, polyvinylidene fluoride or expanded polytetrafluoroethylene. The prepared nanometer composite anti-adhesion surgical mesh has a composite layer structure and comprises a warp mesh layer and a nanofiber membrane layer adjacent to each other, the thickness of the nanofiber membrane is 0.7-1.8 microns, and the diameter of fibers in the nanofiber membrane is 254-597nm. The preparation method disclosed by the invention does not need an adhesive, and is simple in process, free in toxic or harmful substances, safe,