吡啶硫酮、其药物组合物及其用于治疗增殖性、炎症性、神经变性或免疫-介导的疾病的治疗用途

本文提供吡啶硫酮例如式I的化合物及其药物组合物。本文还提供其用于治疗、预防或改善增殖性、炎症性、神经变性或免疫介导的疾病(例如多发性硬化症)的一种或多种症状的方法。 Provided herein are pyridinethiones, for example, a compound of Formula (I), and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more...

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Zusammenfassung:本文提供吡啶硫酮例如式I的化合物及其药物组合物。本文还提供其用于治疗、预防或改善增殖性、炎症性、神经变性或免疫介导的疾病(例如多发性硬化症)的一种或多种症状的方法。 Provided herein are pyridinethiones, for example, a compound of Formula (I), and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a proliferative, inflammatory, neurodegenerative, or immune-mediated disease (e.g., multiple sclerosis).