METHODS FOR REDUCING PERINATAL MORBIDITY AND/OR MORTALITY

A method for preventing or reducing the risk of perinatal or neonatal morbidity and mortality caused by antenatal inflammation in humans is described. This method is based on the administration of a compound of formula I or a pharmaceutically acceptable salt thereof to an expectant human mother suffering from antenatal fetal inflammation. The method prevents or reduces the risk of organ damages, including brain, lung and intestinal damages, and sequelae therefrom, in the neonates, as well as the risk of neonatal death. 描述了用于预防或减少在人类中由产前炎症导致的围产期或新生儿发病和死亡的风险的方法。该方法基于向患有产前胎儿炎症的待产人类母亲给药式I的化合物或其药学上可接受的盐。该方法预防或减少了新生儿中的器官损害，包括脑、肺和肠损害，和由此产生的后遗症的风险，以及新生儿死亡的风险。