Inactivation method for foot and mouth disease virus

The invention provides an inactivation method for a foot and mouth disease virus. The method comprises the following steps: adding a psoralen compound to foot and mouth disease virus cell culture solution, and performing illumination treatment, to obtain inactivated foot and mouth disease virus solution. The method has the following beneficial effects: 1, an inactivation process is greatly simplified and inactivation process time is shortened; 2, stability of the inactivation process is improved; 3, antigen loss is reduced; 4, compared with other inactivators, psoralen is non-toxic without causing an immune side reaction to animals; and 5, the method has the effects of eliminating other bacteria and viruses, is beneficial to improve anti-fouling performance of a vaccine, and capable of improving product quality, and prolonging storage time. 本发明提供了种口蹄疫病毒的灭活方法，包括以下步骤：在口蹄疫病毒细胞培养液中加入补骨脂素类化合物，然后进行光照处理，即得灭活的口蹄疫病毒溶液。本发明具有如下的有益效果：1、极大简化灭活工艺缩短了灭活工艺时间；2、提高了灭活工艺稳定性；3、减少抗原损失；4、相比其他灭活剂补骨脂素无毒，不会对动物造成免疫副反应；5、有消除其他细菌和病毒的作用，有