Controlled-release preparation using live erythrocyte to load betamethasone sodium phosphate and preparation method and application thereof

The invention belongs to the technical field of pharmacy, and particularly relates to a controlled-release preparation using live erythrocyte to load betamethasone sodium phosphate and a preparation method and application thereof. The controlled-release preparation comprises live erythrocyte and bet...

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Hauptverfasser: ZHANG XIUMEI, GUO PENGCHENG, QIU MINGFENG, LIAN YUMEI, YUAN WEI'EN, XU ENGE, SU JING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of pharmacy, and particularly relates to a controlled-release preparation using live erythrocyte to load betamethasone sodium phosphate and a preparation method and application thereof. The controlled-release preparation comprises live erythrocyte and betamethasone sodium phosphate, wherein the betamethasone sodium phosphate is enclosed into the live erythrocyte. Compared with free medicines, the controlled-release preparation has the advantages that the obvious controlled-release function is realized, and the problem of short maintaining time of plasma concentration after injection of betamethasone sodium phosphate can be solved; after the controlled-release preparation enters a body, the medicine can be slowly released, and the medicine effectmaintains for about 5 d; by slowly releasing the betamethasone sodium phosphate, the problem of quick reduction of plasma concentration of the traditional injection of betamethasone sodium phosphateis solved, and the problem