Benzotroponoid compounds and preparation method and applications thereof

The invention belongs to the field of drugs or health care products, and specifically relates to benzotroponoid compounds and a preparation method and applications thereof. The structure of the benzotroponoid compounds is represented in the description. Compared with theaflavin, theaflavin-3-gallate...

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1. Verfasser:	WEN YAOLIN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention belongs to the field of drugs or health care products, and specifically relates to benzotroponoid compounds and a preparation method and applications thereof. The structure of the benzotroponoid compounds is represented in the description. Compared with theaflavin, theaflavin-3-gallate, theaflavin-3'-gallate, and theaflavin-3,3'-digallate, the provided benzotroponoid compounds have abetter effect on inhibiting the weight gain of mice and reducing the blood fat, and have a better curative effect on the non-alcoholic fatty liver disease. 本发明属于药品或保健品领域，具体涉及苯并卓酚酮类似物及其制备方法与用途。所述苯并卓酚酮类似物具有如下结构：本发明化合物抑制小鼠体重增加的效果显著优于茶黄素、茶黄素-3-没食子酸酯、茶黄素-3'-没食子酸酯和茶黄素-3,3'-双没食子酸酯抑制小鼠体重增加的效果；其降血脂的效果显著优于茶黄素、茶黄素-3-没食子酸酯、茶黄素-3'-没食子酸酯和茶黄素-3,3'-双没食子酸酯降血脂的效果；其对非酒精性脂肪肝的治疗效果显著优于茶黄素、茶黄素-3-没食子酸酯、茶黄素-3'-没食子酸酯和茶黄素-3,3'-双没食子酸酯对非酒精性脂肪肝的治疗效果。