Pyrimidinedione derivative capable of inhibiting monocarboxylate transporter

The invention relates to a pyrimidinedione derivative capable of inhibiting a monocarboxylate transporter, the pyrimidinedione derivative is a formula (I) compound and/or a pharmaceutically acceptablesalt thereof, and/or a stereoisomer thereof, and/or a solvate thereof, the compound has the effect o...

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Bibliographische Detailangaben
Hauptverfasser:	LEI WENBO, WU KUNCAN, LIU CAIPING, HE ZHIQIN, DENG JIE, ZOU YANYE, XU LIYAN, LIAO YONG, FAN BIN, ZHOU CHANGBING, YUAN QUAN, LEI HUANGSHU
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to a pyrimidinedione derivative capable of inhibiting a monocarboxylate transporter, the pyrimidinedione derivative is a formula (I) compound and/or a pharmaceutically acceptablesalt thereof, and/or a stereoisomer thereof, and/or a solvate thereof, the compound has the effect of inhibiting the activity of the monocarboxylate transporter, and also comprises a pharmaceutical composition containing the formula (I) compound and the use of the pharmaceutical composition in treatment. 本发明涉及种抑制单羧酸转运蛋白的嘧啶二酮衍生物，为式（I）化合物和/或其药学上可接受的盐，和/或其立体异构体，和/或其溶剂合物，该化合物具有抑制单羧酸转运蛋白活性，还包括含有式（I）化合物的药物组合物以及它们在治疗中的用途。