Preparation method of anti-inflammation, thermal therapy and imaging combined targeted nano material and product thereof

The invention provides a preparation method of an anti-inflammation, thermal therapy and imaging combined targeted nano material and a product thereof. Phenolic resin is used as a prepolymer, a segmented copolymer is added for reaction and carbonization, and mesoporous carbon nano particles are obtained. The nano particles with mesoporous carbon modified by PVP adsorb an anti-inflammatory drug anda CT contrast agent to obtain the antiinflammation, thermal therapy and imaging combined targeted nano material. The heat effect produced by mesoporous nano carbon spheres under near-infrared rays isutilized to make the temperature of tissue rise and promote cancer cell death. In addition, the added anti-inflammatory drug effectively inhibits tumor growth, passive targeted effect makes the imaging effect of the supported CT contrast agent better. 本发明提供了种消炎、热疗与成像相结合的靶向纳米材料的制备方法及其产品，将以酚醛树脂为预聚体，加入嵌段共聚物反应并碳化得到介孔碳纳米颗粒。介孔碳经PVP修饰后的纳米颗粒吸附消炎药与CT造影剂，得到消炎、热疗与成像相结合的纳米材料。本发明利用介孔纳米碳球在近红外下所产生的热效应，使组织升温，加速肿瘤细胞死亡，另外加入消炎药有效抑制肿瘤的生长，被动靶