5-(furan-2'-carbonyl)-2, 3-dihydro-1H-pyrrolizin-7-carboxylic acid and derivative thereof

The invention belongs to the technical field of medicines and specifically relates to a compound shown in the formula (I), pharmaceutically acceptable salt of the compound, easily hydrolyzed ester ofthe compound, a hydrate of the compound and a hydrate of the ester or the salt of the compound. The invention also relates to a preparation method of the compounds, a pharmaceutical composition containing the compounds and application of the compounds in preparation of drugs for treating tumors and prevention of diseases induced by in-vivo excess release of NO. 本发明属于医药技术领域，具体涉及式(I)所示的化合物、其药学上可接受的盐、其易水解的酯、其水合物，及其酯或盐的水合物：本发明还涉及这些化合物的制备方法，含有这些化合物的药物组合物，以及这些化合物在用于制备治疗肿瘤药物以及防治因NO在体内过度释放诱发的疾病中的用途。式（I）.。