Extracting preparation method of fimbriatone
The invention discloses an extracting preparation method of fimbriatone. The method comprises the following steps of extracting by alcohol; extracting by a petroleum ether-chloroform solution, and concentrating; removing impurities in an alkaline ring-opening way; purifying fimbriatone in an acid cl...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses an extracting preparation method of fimbriatone. The method comprises the following steps of extracting by alcohol; extracting by a petroleum ether-chloroform solution, and concentrating; removing impurities in an alkaline ring-opening way; purifying fimbriatone in an acid closed-loop way; applying positive-phase column chromatography to a closed-loop fimbriatone crude product, eluting by a chloroform-methanol solution, collecting an eluting solution containing fimbriatone, and crystallizing by a solvent method, so as to obtain the fimbriatone. The extracting preparation method has the advantages that the method is simple, the operation is easy, and the method is suitable for the industrialized production and the popularization and application.
本发明公开了种流苏菲的提取制备方法,该方法经过醇提、石油醚-氯仿溶液萃取浓缩,碱性开环除杂,酸性环合纯化流苏菲,环合流苏菲粗品过正相柱层析用氯仿-甲醇液洗脱,收集含流苏菲的洗脱液,溶剂法结晶,制得流苏菲;本发明方法简单易操作,适于工业化生产和推广应用。 |
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