Combination therapy involving antibodies against Claudin 18.2 for treatment of cancer

The present invention provides a combination therapy for effectively treating and/or preventing diseases associated with cells expressing CLDN18.2, including cancer diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-...

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Hauptverfasser: STEFAN DENIS JACOBS, ZLEM TRECI, MAGDALENA JADWIGA UTSCH, CHRISTIANE R STADLER, RITA MITNACHT-KRAUS, CORNELIA ADRIANA MARIA HEINZ, UGUR SAHIN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention provides a combination therapy for effectively treating and/or preventing diseases associated with cells expressing CLDN18.2, including cancer diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder and metastases thereof. 本申请涉及用于治疗癌症的涉及针对密蛋白18.2之抗体的联合治疗。本发明提供了种用于有效治疗和/或预防与表达CLDN18.2细胞相关之疾病的联合治疗,所述疾病包括癌症疾病,例如胃癌、食管癌、胰腺癌、肺癌、卵巢癌、结肠癌、肝癌、头颈癌和胆囊癌及其转移。