Pharmacodynamic application of schizocapsa plantaginea saponin in preparing drug for treating hepatic fibrosis

The invention discloses a pharmacodynamic application of schizocapsa plantaginea saponin in preparing a drug for treating hepatic fibrosis. The invention researches hepatic fibrosis resistance of schizocapsa plantaginea saponin for the first time. In vitro and in vivo experiments verify that the schizocapsa plantaginea saponin has a relatively good action of inhibiting proliferation of hepatic stellate cells and activity of resisting hepatic fibrosis. The schizocapsa plantaginea saponin can be used as an active component of the hepatic fibrosis resistant drug, and has a wide application. The research finds that the schizocapsa plantaginea saponin shows good hepatic fibrosis resistant action from in vivo and in vitro experiments and is a novel drug with a potential value for treating chemical hepatic fibrosis. 本发明公开了裂果薯皂苷在制备抗肝纤维化药物中的药效学应用。首次对裂果薯皂苷进行了抗肝纤维化的研究,体外和体内实验表明,其具有较强的抑制肝星状细胞增殖的作用、抗肝纤维化活性，可以作为抗肝纤维化药物的活性成分，具有广泛的用途，本发明研究发现该裂果薯皂苷从体内和体外实验均表现出良好的抗肝纤维化作用，是治疗化学性肝纤维化的种非常有潜在价值的新药。