Synthetic method of anastrozole key intermediate

The invention provides a preparation method of an anastrozole key intermediate (I) shown in the description. 3, 5-toluene dihalide (II) and 2-methyl-2-cyanopropionic acid (III) are taken as raw materials and subjected to one-step reaction in the presence of alkali, a solvent and a copper catalyst, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WEI WENDENG, MA BO, ZHOU YUBAO, ZHENG LIUJUN, WANG HUI
Format: Patent
Sprache:chi ; eng
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