ANTIBODY SPECIFICALLY BINDING TO ANTIGEN DERIVED FROM MYCOBACTERIA OR ANTIGEN-BINDING FRAGMENT THEREOF

The invention relates to an antigen-binding fragment which specifically binds to CFP-10 or Ag85B which is an antigen derived from mycobacteria, a polynucleotide encoding the same, a recombinant vectorcomprising the polynucleotide, and a host cell comprising the recombinant vector. When the antigen-b...

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Bibliographische Detailangaben
Hauptverfasser:	PARK TAE-JUNG, KIM HWA-JUNG, SHIN HYUNUL
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to an antigen-binding fragment which specifically binds to CFP-10 or Ag85B which is an antigen derived from mycobacteria, a polynucleotide encoding the same, a recombinant vectorcomprising the polynucleotide, and a host cell comprising the recombinant vector. When the antigen-binding fragment of the invention is used, CFP-10 or Ag85B, as an antigen derived from mycobacteria,can be detected with high sensitivity, it is possible to develop a kit capable of detecting mycobacteria rapidly and accurately. 本发明涉及与作为来自于分枝杆菌之抗原的CFP-10或Ag85B特异性结合的抗原结合片段、编码它的多核苷酸、包含所述多核苷酸的重组载体、以及包含所述重组载体的宿主细胞。当使用本发明的抗原结合片段时，可以以高灵敏度检测作为来自于分枝杆菌之抗原的CFP-10或Ag85B，可开发能够迅速且准确地检测分枝杆菌的试剂盒。