Derivatives of pyrroloimidazole or analogues thereof which are useful for the treatment of inter alia cancer

Present invention relates to novel heterocyclic compounds as indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3-dioxygenase (TDO) modulators. Compounds of the present invention inhibit tryptophandegradation by modulating IDO and/or TDO. Formula (I) The invention further relates to the process of their preparation, pharmaceutical composition and their use in modulating the activity of indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3- dioxygenase (TDO). The compounds of the invention can be used alone or in combination for the treatment of conditions that benefits from the inhibition of tryptophan degradation. 本发明涉及作为吲哚胺2，3-双加氧酶(IDO)和/或色氨酸2，3-双加氧酶(TDO)调节剂的新的杂环化合物。本发明化合物通过调节IDO和/或TDO来抑制色氨酸降解。本发明还涉及其制备方法、药物组合物及其在调节吲哚胺2，3-双加氧酶(IDO)和/或色氨酸2，3-双加氧酶(TDO)活性中的用途。本发明化合物可单独或组合使用，用于治疗受益于抑制色氨酸降解的病症。