CD31SHED agonists for use in prevention and/or treatment of reperfusion injury

The present invention relates to CD31shed agonists for use in the prevention and/or treatment of reperfusion injury. These CD31shed agonists are peptides or peptidomimetics thereof that are able to restore CD31 signaling in cells bearing a truncated form of CD31 called CD31shed. The CD31shed agonist...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	GALIGIURI GIUSEPPINA, NICOLETTI ANTONINO, MICHEL JEAN-BAPTISTE
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to CD31shed agonists for use in the prevention and/or treatment of reperfusion injury. These CD31shed agonists are peptides or peptidomimetics thereof that are able to restore CD31 signaling in cells bearing a truncated form of CD31 called CD31shed. The CD31shed agonists according to the invention particularly protect from organ damages caused by reperfusion used to treat ischemia. 本发明涉及用于再灌注损伤的预防和/或治疗的CD31激动剂。这些CD31激动剂是能够恢复携带称为CD31的截短形式的CD31的细胞中的CD31信号传导的肽或其肽模拟物。根据本发明的CD31激动剂特别保护器官免受用于治疗缺血的再灌注引起的损伤。