COMPOSITIONS AND METHODS FOR INCREASING IRON INTAKE IN A MAMMAL

Compositions containing iron, buffering agent and denatured protein have been prepared that are capable of increasing serum iron in a subject. For example, spray dried microbeads have been prepared containing iron entrapped within a protein matrix and unbound iron in a buffered composition that provides a gastroprotective effect, preserves iron in the more available Fe2+ form and improves iron bioavailability in humans relative to previously known vehicles for delivering iron to a subject. 已经制备了含有铁、缓冲剂和变性蛋白质的组合物，其能够增加受试者中的血清铁。举例来说，已经制备了经喷雾干燥的微珠，所述微珠含有包埋在蛋白质基质中的铁和缓冲组合物中的未结合的铁，所述缓冲组合物提供胃保护作用、以更具可用性的Fe的形式保存铁并且相对于用于将铁递送给受试者的先前已知的媒介提高人类体内的铁生物利用度。