Novel medical application of Nifuroxazide

The invention discloses novel medical application of Nifuroxazide, namely the novel application of the Nifuroxazide as a medicine for treating psoriasis. The Nifuroxazide disclosed by the invention adopts peritoneal injection for treatment; the result shows that the Nifuroxazide can obviously reliev...

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Bibliographische Detailangaben
Hauptverfasser: HU HUA, FU DANDAN, TIAN CHENRUI, DUAN YAJU, GUO SHENG, TIAN ZHONGWEI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses novel medical application of Nifuroxazide, namely the novel application of the Nifuroxazide as a medicine for treating psoriasis. The Nifuroxazide disclosed by the invention adopts peritoneal injection for treatment; the result shows that the Nifuroxazide can obviously relieve the formation of local scale of psoriasis sample skin lesion, erythema and incrassation induced byimiquimod, and inhibits the phosphorylation of stat3 in skin lesion tissues and the generation of TNF-alpha in serum. The Nifuroxazide is used to treat skin keratinocytes to form HaCaT cells; the result shows that the Nifuroxazide can significantly inhibit the proliferation of the HaCaT cells and inhibit the phosphorylation of HaCaT cell stat3. Therefore, the Nifuroxazide is used for treating thepsoriasis, and can be used for effectively inhibiting the proliferation of skin keratinocytes and relieving the inflammation degree of skin; in addition, a Nifuroxazide preparation has the advantagesof safety, no toxicity and