Compound for positron imaging, intermediate and preparation method thereof, and imaging agent containing compound

The invention relates to a compound. The compound has a structure as shown in a formula I or a formula II which are described in the specification. In the formula I and the formula II, R is selected from the group consisting of C1-12 alkyl groups with at least one 18F substituent, -(CH2O)x-CH3, -(CH2CH2O)y-CH2CH3 and -(CH2CH2CH2O)z-CH2CH2CH3, wherein x is an integer in a range of 1 to 10; y is aninteger in a range of 1 to 5; and z is an integer in a range of 1 to 3. The invention also relates to an intermediate used for preparing the compound, a preparation method for the compound, and a positron imaging agent containing the compound. The compound provided by the invention is simple to prepare, has good stability and large radiation amount, and can specifically target a tumor region withan abnormally-activated PI3K pathway. 本发明涉及种式I或式II所示的化合物，其中，R为具有至少个F取代基的C的烷基、-(CHO)-CH、-(CHCHO)-CHCH或-(CHCHCHO)-CHCHCH，其中x为1-10的整数，y为1-5的整数，z为1-3的整数。本发明还涉及用于制备所述化合物的中间体，所述化合物的制备方法以及包含所述化合物的正电子显像剂。本发明的化合物制备简单，稳定性好，放射量高，并且能够特异性靶