Pantoprazole sodium enteric-coated tablet and preparation method thereof

The invention relates to the technical field of drugs and preparation thereof, in particular to a pantoprazole sodium enteric-coated tablet and a preparation method thereof. The pantoprazole sodium enteric-coated tablet is prepared from the following matters of, by weight, 1-15 parts of pantoprazole sodium sesquihydrate, 1-6 parts of PH regulators, 0.1-2 parts of enteric coated polymer, 10-40 parts of filling agents, 0.1-2 part of lubricating agents, 3-8 part of bonding agents, 3-12 parts of disintegrating agents, 0-0.05 part of coloring agent, 0.05-1 part of antioxidant, and 0.05-2 parts of plasticizers. According to the pantoprazole sodium enteric-coated tablet, a coat can be maintained to be complete in the stomach, drugs are smoothly released in an intestinal tract, pantoprazole sodiumcan be prevented from being degraded in gastric acid and can also be quickly disintegrated and precipitated in the intestinal tract, and thus symptoms of gastrointestinal ulcer patients are quickly alleviated; and the drug d