Novel substituted salicylic acids

Het-NR-So2-Ph2-A-Ph1-(COOH)(OH) compound and its tautomer, salt, solvate, C1-6 alkyl ester, and medicinal composition containing the compound are disclosed. In the formula, ph1 and ph2 are benzene ring with adjacent carboxyl and hydroxyl, Het is opt. substituted heterocycle with conjugated double bo...

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Bibliographische Detailangaben
Hauptverfasser: THOMAS BERGLINDH, HUBERT AGBACK, LEIF AHRGREN
Format: Patent
Sprache:eng
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Zusammenfassung:Het-NR-So2-Ph2-A-Ph1-(COOH)(OH) compound and its tautomer, salt, solvate, C1-6 alkyl ester, and medicinal composition containing the compound are disclosed. In the formula, ph1 and ph2 are benzene ring with adjacent carboxyl and hydroxyl, Het is opt. substituted heterocycle with conjugated double bonds and connected to N in NR, A (not azo) is bridge stable to reduction, and R is hydrogen or lower alkyl. Its medicinal composition can treat anto-immunity disease.