Application of metformin to reversion of cisplatin resistance of ovarian cancer

The invention discloses application of metformin to reversion of cisplatin resistance of ovarian cancer. The metformin can be used for preparing drugs for preventing and/or treating the ovarian cancer. The metformin can also be used for preparing products with any of the following functions: 1) inhibiting the proliferation of ovarian cancer cells; 2) accelerating the apoptosis of the ovarian cancer cells; 3) delaying the growth of the ovarian cancer cells; and the ovarian cancer is resistant to cisplatin. The metformin is applied together with a chemotherapeutic drug, and the chemotherapeuticdrug is the cisplatin. The experimental result of a nude mice model with chemotherapy-resistant ovarian cancer (ovarian cancer cells are CP70 cells and C13K cells, and the chemotherapy drug is the cisplatin) shows that the metformin changes the growth of chemotherapy-resistant ovarian cancer cells by regulating cell cycle (delaying cell growth), accelerating cell apoptosis, inhibiting cell proliferation and the like. An i