Heterotricyclic derivatives

Heterotricyclic derivatives

PCT No. PCT/JP93/00090 Sec. 371 Date Jul. 26, 1994 Sec. 102(e) Date Jul. 26, 1994 PCT Filed Jan. 26, 1993 PCT Pub. No. WO93/15083 PCT Pub. Date Aug. 5, 1993 wherein R1 is hydrogen, lower alkyl, lower alkoxy, lower alkylthio, halogen, nitro, amino or protected amino, R2 is hydroxy, protected hydroxy,...

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Hauptverfasser: HATSUYA NAKAMURA, MASAAKI MATSUO, KIYOSHI TSUJI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:PCT No. PCT/JP93/00090 Sec. 371 Date Jul. 26, 1994 Sec. 102(e) Date Jul. 26, 1994 PCT Filed Jan. 26, 1993 PCT Pub. No. WO93/15083 PCT Pub. Date Aug. 5, 1993 wherein R1 is hydrogen, lower alkyl, lower alkoxy, lower alkylthio, halogen, nitro, amino or protected amino, R2 is hydroxy, protected hydroxy, halogen, amino or protected amino, R3 is hydrogen or an organic group, R4 R is hydrogen or lower alkyl, R8 is hydrogen or lower alkyl, and -Z- is -O- or a group of the formula: (in which n is 0, 1 or 2), and pharmaceutically acceptable salts thereof which are useful as a medicament.