Preparation method of burn cream taking hyaluronic acid/graphene oxide nano-composite hydrogel as carrier

The invention relates to a preparation method of a burn cream, in particular to a preparation method of a burn cream taking hyaluronic acid/graphene oxide nano-composite hydrogel as a carrier. The method comprises firstly preparing tyramine grafted hyaluronic acid, dissolving the tyramine grafted hy...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: MENG YING, HU WANNING, YAN JINYIN
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to a preparation method of a burn cream, in particular to a preparation method of a burn cream taking hyaluronic acid/graphene oxide nano-composite hydrogel as a carrier. The method comprises firstly preparing tyramine grafted hyaluronic acid, dissolving the tyramine grafted hyaluronic acid in a PBS solution of graphene oxide, forming a mixed solution, adding horse radish peroxidase (HRP) and H2O2, rapidly stirring, and allowing standing still for a reaction for 30-60 minutes at the temperature of 20-40 DEG C, thereby obtaining the hyaluronic acid/graphene oxide nano-composite hydrogel. The composite hydrogel is blended with badger fat, Chinese angelica, angelica dahurica, lithospermum, sangusis draconis, liquorice, cortex phellodendri, coptis chinensis, radix scutellariae and borneol according to a stirring method to form the cream, the cream is a cream drug for exterior application, takes hyaluronic acid/graphene oxide and an antibacterial anti-cicatricial repairing drug as the basis,