Nanometer magnetic particles covered with erythrocyte membranes, and preparation method and uses thereof

The invention provides nanometer magnetic particles covered with erythrocytes, particularly nanometer magnetic particles covered with erythrocyte membranes, and a preparation method and uses thereof.The invention also provides the uses of the nanometer magnetic particles in preparation of a myocardi...

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Hauptverfasser: GU CHANGGUO, DUAN JIACHUAN, FAN YUANQIAO, FAN DAIMING
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creator GU CHANGGUO
DUAN JIACHUAN
FAN YUANQIAO
FAN DAIMING
description The invention provides nanometer magnetic particles covered with erythrocytes, particularly nanometer magnetic particles covered with erythrocyte membranes, and a preparation method and uses thereof.The invention also provides the uses of the nanometer magnetic particles in preparation of a myocardial infarction animal model. The myocardial infarction animal model is of great value for myocardialinfarction prevention, diagnosis and treatment. Thinking outside a traditional train of thought of preparing myocardial infarction animal models through surgical operation coronary artery ligation, magnetic-carrier artificial erythrocytes are constructed and fed back into an animal body, and local aggregation of the magnetic-carrier artificial erythrocytes is controlled by an external magnetic field to cause local vessel obstruction of heart so as to induce local myocardial infarction. Major trauma caused by blood vessel ligation is completely avoided, and the animal model which can truly simulate a myocardial infarct
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subjects AGRICULTURE
ANIMAL HUSBANDRY
CARE OF BIRDS, FISHES, INSECTS
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
HYGIENE
MEDICAL OR VETERINARY SCIENCE
NEW BREEDS OF ANIMALS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR
TRAPPING
title Nanometer magnetic particles covered with erythrocyte membranes, and preparation method and uses thereof
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