Nucleic acid synthesis solid phase carrier, preparation method, nucleic acid synthesis device containing carrier and nucleic acid synthesis method

The invention provides a nucleic acid synthesis solid phase carrier. A preparation method of the nucleic acid synthesis solid phase carrier comprises the following steps: preparing water-based magnetic fluid, adding the fluid into a silica sol precursor containing soft magnetic material powder, standing to produce gel, and performing heat treatment on the gel at the temperature of 600-900 DEG C for 1-3 hours so as to obtain magnetic control pore glass beads MCPG. The MCPG is activated, and various nucleotide monomers can be connected. The invention further relates to a nucleic acid synthesis device which comprises the MCPG, an electromagnetic rod and a reaction plate, wherein the electromagnetic rod is formed by embedding an electromagnet into a shell. The reaction rod is loaded with the activated MCPG, and the reaction rod is inserted into the reaction plate of each reaction plate. In each reaction tank, desorption and release of the MCPG can be realized by controlling power on-off ofthe electromagnet, and s