Salicylic acid compound as well as preparation method and application thereof

The invention discloses a salicylic acid compound with a structure represented by formula (I) or a pharmaceutically acceptable salt thereof or a stereoisomer thereof or a prodrug molecule thereof, thecompound has good water solubility, good targeting and significant inhibition to tumor cells, and less toxicity to normal cells, thus having a good prospect in the application of anti-tumor drugs, the invention also discloses a preparation method of the compound, the preparation method provided by the invention has good controllability and high yield, and the yield of the compound is 80% or above. 本发明公开了具有式(Ⅰ)所示结构的水杨酸类化合物或其药学上可接受的盐或其立体异构体或其前药分子。该类化合物具有较好的水溶性，其对肿瘤细胞具有较好的靶向性和显著的抑制作用，且其对正常细胞的毒性小，在抗肿瘤药物方面具有较好的应用前景。本发明还公开了该类化合物的制备方法，本发明制备方法的可控性好，产率高，其产率为80％以上。