Applications of bitter and cold medicines or extract products of bitter and cold medicines in preparation of medicines or health care products used for adjusting body biorhythm gene protein expression

The invention belongs to the field of Chinese herbal medicine, and more specifically relates to applications of bitter and cold medicines or extract products of the bitter and cold medicines in preparation of medicines or health care products used for adjusting body biorhythm gene protein expression. High-fat diet is capable of changing the biorhythm of obesity rats, somnolence and diet reductionare caused; high-fat diet is capable of inhibiting rat biorhythm gene Arntl, Per3 and Clock transcription activity and expression, inhibiting liquid catabolism, promoting accumulation of fat in bodies, and increasing the content of triglycerides in blood. The bitter and cold medicines (Rhizoma Coptidis, root of large-flowered skullcap, phellodendron, radix gentianae, Sophora flavescens, and the like) are capable of reversing the biorhythm genes, and reducing the level of triglycerides in body serum. 本发明涉及中草药领域，具体涉及苦寒药或其提取物用于制备调节机体生物节律基因蛋白表达的药物或保健品的用途。高脂饮食造成的肥胖大鼠其生物节律发生了改变，嗜睡、饮食减少。高脂饮食能够抑制大鼠生物节律基因Arntl、Per3和Clock的转录活性和